Browsing by Subject "Extracellular matrices"
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Article
Atomic Force Microscopy Probing of Cancer Cells and Tumor Microenvironment Components
(2016)Cancer cells have different characteristics from normal cells in terms of morphology, cell–cell interactions, cytoskeleton organization, cell growth rates, and cell-extracellular matrix interactions. Although the clarification ...
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Article
Regional elastic modulus measurements of the ex-vivo murine heart using atomic force microscopy
(2013)Stiffness is an important mechanical index for characterisation of human and animal cells, tissues and intact organs. This study presents efforts for passive mechanical characterisation of the ex-vivo C57BL/6 murine heart ...
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Article
Sonic-hedgehog pathway inhibition normalizes desmoplastic tumor microenvironment to improve chemo- and nanotherapy
(2017)Targeting the rich extracellular matrix of desmoplastic tumors has been successfully shown to normalize collagen and hyaluronan levels and re-engineer intratumoral mechanical forces, improving tumor perfusion and chemotherapy. ...